Checkpoint Controls and Cancer: Volume 1: Reviews and Model Systems

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Authors: Hiroshi Nojima (auth.), Axel H. Schönthal PhD (eds.)
Publisher: Humana Press
Genre: Medicine > Oncology
Pages: 318
Language: english
Year: 2004
ISBN 10: 1588292142
ISBN 13: 9781588292148
Series: Methods in Molecular Biology 280
Edition: 1
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Synopsis

Intracellular checkpoint controls constitute a network of signal transduction pathways that protect cells from external stresses and internal errors by means of cell cycle arrest, DNA repair, or apoptosis. Failure of this machinery can lead to embryonic death, genetic diseases,...